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Polynucelotides

About

Polynucleotides are injectable skin boosters made from highly purified DNA fragments, usually sourced from salmon. They aid in skin repair by improving cell function and stimulating collagen and elastin production. This makes the skin look healthier, firmer, and more hydrated over time. Polynucleotides are especially useful for treating tired, thin, or ageing skin. highly effective in treating skin laxity, dullness, fine lines, and signs of photoageing, particularly in delicate areas.

How are polynucelotides different from Profhilo?

Both treatments improve skin quality, but they work in different ways.

Feature

Profhilo

Polynucelotides

What it is

Injectable skin booster with high-purity hyaluronic acid

Injectable skin regenerating treatment made from purified fish DNA fragments

Primary Action

Deep hydration, skin tightening, and stimulation of collagen + elastin

Tissue regeneration, repair, and stimulation of fibroblasts + collagen

Where it works

Spreads evenly under the skin to improve overall skin quality

Works more locally, focusing on repairing and strengthening treated areas

Best for

- Mild skin laxity

- Crepey texture

- Dehydrated or dull skin

- General skin ageing

- Delicate areas (e.g., under-eyes)

- Fine lines, early wrinkles

- Thin or fragile skin

- Signs of photoageing

Volume added

None – improves skin firmness and tone

None – supports skin structure and density

Key difference

Focuses on hydration and skin firmness

Focuses on regeneration and cellular repair

How many sessions will I need?

A typical protocol includes 2 - 3 sessions spaced 3 - 4 weeks apart, depending on skin quality and the area being treated. Maintenance sessions every 6 months are recommended for ongoing skin support and long-term improvement.

When will I see results?

Improvements in skin tone, texture, and hydration typically begin to show within 2–3 weeks, but the full regenerative effects develop gradually over 4–8 weeks and continue to improve with repeated treatments.

Is there any downtime?

Downtime is minimal. Mild swelling, redness, or small bumps at the injection sites may occur and usually settle within 24 - 48 hours. Bruising is possible, particularly in delicate areas like under the eyes (can be covered with make up after 24 hours). Most patients return to normal activities the same day.